SHX-011 is a combo patch of racemic ketamine and scopolamine for treatment of MDD. Numerous data demonstrated the synergic anti-depression effect of ketamine and scopolamine. The objective of SHX-011 is to develop a combo patch for racemic ketamine and scopolamine, by offering better pharmaceutical effect and the conveniency to dose these two drugs. Once the performance of SHX-001 is confirmed in Phase 2b, SHX-011 can be assessed initially in a phase 2 proof-of-concept study by applying SHX-001 and commercially available scopolamine patches.
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